Stat4(Phospho Tyr693) Polyclonal Antibody

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors| STAT family members are phosphorylated by the receptor associated kinases| and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes| and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

The Stat4(Phospho Tyr693) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated Tyr693 residue on the Stat4 protein. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target epitope.

The Stat4 protein plays a crucial role in the signal transduction pathway, particularly in the regulation of immune responses and cytokine signaling. Phosphorylation of Tyr693 residue on Stat4 is known to be a key event in the activation and subsequent nuclear translocation of this protein, leading to the transcriptional regulation of various genes involved in immune response modulation.

The Stat4(Phospho Tyr693) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated Tyr693 residue on Stat4 protein in various biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing wastage. The Stat4(Phospho Tyr693) Polyclonal Antibody is compatible with a wide range of experimental conditions and can be used in both research and clinical settings.

In summary, the Stat4(Phospho Tyr693) Polyclonal Antibody is a valuable tool for researchers and clinicians studying the role of Stat4 protein in immune response regulation. Its high specificity, sensitivity, and versatility make it an essential component in various experimental techniques, facilitating accurate and reliable analysis of phosphorylated Tyr693 residue on Stat4 protein.