Stat3 Polyclonal Antibody

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors| STAT family members are phosphorylated by the receptor associated kinases| and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs| EGF| IL5| IL6| HGF| LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli| and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper

The Stat3 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Signal Transducer and Activator of Transcription 3 (Stat3) protein. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity. It has been extensively validated for various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Stat3 Polyclonal Antibody exhibits exceptional performance in detecting endogenous levels of Stat3 protein in a wide range of species, including human, mouse, and rat. It recognizes both the phosphorylated and non-phosphorylated forms of Stat3, enabling comprehensive investigation of its activation status. With its superior specificity, this antibody allows for precise and accurate quantification of Stat3 expression levels in various tissues and cell types.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effective and efficient experiments. The Stat3 Polyclonal Antibody is manufactured under strict quality control standards, guaranteeing consistent and reproducible results. It exhibits minimal cross-reactivity with other related proteins, ensuring reliable and specific detection of Stat3.

In summary, the Stat3 Polyclonal Antibody is an indispensable tool for researchers studying the role of Stat3 in various biological processes. Its exceptional specificity, sensitivity, and versatility make it an ideal choice for a wide range of applications, facilitating in-depth investigations into the signaling pathways involving Stat3.