Stat1(Phospho Tyr701) Polyclonal Antibody

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors| STAT family members are phosphorylated by the receptor associated kinases| and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha| interferon-gamma| EGF| PDGF and IL6. This protein mediates the expression of a variety of genes| which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

 The Stat1(Phospho Tyr701) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated Stat1 at Tyr701. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

The Stat1 protein plays a crucial role in the regulation of various cellular processes, including immune response, cell growth, and differentiation. Phosphorylation of Stat1 at Tyr701 is a key event in the activation of its transcriptional activity and subsequent downstream signaling pathways.

This polyclonal antibody has been extensively validated for its specificity and sensitivity in various experimental settings, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated Stat1 and other related proteins, ensuring accurate and reliable results.

The Stat1(Phospho Tyr701) Polyclonal Antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is provided in a ready-to-use format, eliminating the need for additional reagents or preparation steps.

With its exceptional performance and reliability, the Stat1(Phospho Tyr701) Polyclonal Antibody is an indispensable tool for researchers studying the role of Stat1 phosphorylation in various biological processes. Its high specificity and sensitivity make it an ideal choice for both basic research and clinical applications.