SH-PTP1(Phospho Tyr536) Polyclonal Antibody

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth| differentiation| mitotic cycle| and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains| which act as protein phospho-tyrosine binding domains| and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells| and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with| and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene| which encode distinct isoforms| have been reported.

The SH-PTP1(Phospho Tyr536) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated tyrosine 536 residue in the SH-PTP1 protein. This antibody is produced using advanced polyclonal antibody production techniques, ensuring high affinity and specificity towards the target epitope.

The SH-PTP1 protein, also known as Src homology 2 domain-containing protein tyrosine phosphatase 1, plays a crucial role in various cellular processes, including signal transduction, cell proliferation, and differentiation. Phosphorylation of tyrosine 536 residue in SH-PTP1 has been implicated in the regulation of its enzymatic activity and downstream signaling pathways.

The SH-PTP1(Phospho Tyr536) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated tyrosine 536 residue in SH-PTP1.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering. The antibody is also available in different quantities to meet the specific needs of researchers.

In summary, the SH-PTP1(Phospho Tyr536) Polyclonal Antibody is a valuable tool for researchers studying the role of SH-PTP1 protein and its phosphorylation in cellular processes. Its high specificity, sensitivity, and versatility make it an ideal choice for various applications in molecular biology and biomedical research.