Rad51(Phospho Tyr315) Polyclonal Antibody

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51| and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52| and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2| which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.

The Rad51(Phospho Tyr315) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Rad51 protein phosphorylated at tyrosine 315. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity for the target protein.

Rad51 is a key protein involved in DNA repair and recombination processes. Phosphorylation of Rad51 at tyrosine 315 has been shown to play a crucial role in regulating its activity and function. Therefore, the Rad51(Phospho Tyr315) Polyclonal Antibody is an invaluable tool for researchers studying the molecular mechanisms underlying DNA repair and recombination.

This antibody has been rigorously validated for various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits excellent performance in detecting phosphorylated Rad51 protein in a wide range of sample types, including cell lysates and tissue extracts.

The Rad51(Phospho Tyr315) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size of 100 µg, ensuring ample supply for multiple experiments. The antibody is stored at -20°C to maintain its stability and activity.

With its exceptional specificity, sensitivity, and versatility, the Rad51(Phospho Tyr315) Polyclonal Antibody is an indispensable tool for researchers in the field of DNA repair and recombination. Its reliable performance and ease of use make it an ideal choice for both basic research and clinical applications.