BT Lab
SKU:BT-AP07644
PLC gamma1(Phospho Tyr771) Polyclonal Antibody
PLC gamma1(Phospho Tyr771) Polyclonal Antibody
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The protein encoded by this gene catalyzes the formation of inositol 1|4|5-trisphosphate and diacylglycerol from phosphatidylinositol 4|5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example| when activated by SRC| the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi| where it activates Ras. Also| this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
The PLC gamma1(Phospho Tyr771) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of PLC gamma1 protein phosphorylated at Tyr771 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.
The PLC gamma1 protein plays a crucial role in intracellular signal transduction pathways, particularly in the regulation of phosphoinositide metabolism. Phosphorylation of PLC gamma1 at Tyr771 residue has been implicated in various cellular processes, including cell proliferation, differentiation, and survival.
This polyclonal antibody is rigorously validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated PLC gamma1 protein.
The PLC gamma1(Phospho Tyr771) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage. The antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.
With its exceptional performance and reliability, the PLC gamma1(Phospho Tyr771) Polyclonal Antibody is an indispensable tool for researchers and scientists studying signal transduction pathways and investigating the role of PLC gamma1 protein phosphorylation in various cellular processes.
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