PDK1(Phospho Ser241) Polyclonal Antibody

Catalytic activity:ATP + a protein = ADP + a phosphoprotein.|Phosphorylates and activates not only PKB/AKT| but also PKA| PKC-zeta| RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.|PTM:Phosphorylated on tyrosine and serine/threonine. Phosphorylation on Ser-241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser-241| leading to its own activation.|Belongs to the protein kinase superfamily.|Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDK1 subfamily.|Contains 1 PH domain.|Contains 1 protein kinase domain.|subcellular location:Membrane-associated after cell stimulation leading to its translocation. Tyrosine phosphorylation seems to occur only at the plasma membrane.|subunit:Interacts with TUSC4.|tissue specificity:Appears to be expressed ubiquitously.|

The PDK1(Phospho Ser241) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of PDK1 protein phosphorylated at Serine 241. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

PDK1, also known as 3-phosphoinositide-dependent protein kinase 1, plays a crucial role in various cellular processes, including cell growth, survival, and metabolism. Phosphorylation of PDK1 at Serine 241 is a key regulatory event that modulates its activity and downstream signaling pathways.

The PDK1(Phospho Ser241) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated PDK1 in complex biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage. The PDK1(Phospho Ser241) Polyclonal Antibody is compatible with a wide range of experimental conditions and can be used in both research and clinical settings.

In summary, the PDK1(Phospho Ser241) Polyclonal Antibody is a valuable tool for researchers and clinicians studying the role of PDK1 phosphorylation in cellular processes. Its high specificity, sensitivity, and versatility make it an essential component of any study involving PDK1 signaling pathways.