PDGFR-alpha(Phospho Tyr849) Polyclonal Antibody

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer| composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development| wound healing| and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome| somatic and familial gastrointestinal stromal tumors| and a variety of other cancers.

The PDGFR-alpha(Phospho Tyr849) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of PDGFR-alpha protein phosphorylated at tyrosine 849 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

PDGFR-alpha, also known as platelet-derived growth factor receptor alpha, is a transmembrane receptor tyrosine kinase that plays a crucial role in various cellular processes, including cell proliferation, differentiation, and migration. Phosphorylation of tyrosine 849 residue is an important post-translational modification that regulates the activation and downstream signaling of PDGFR-alpha.

The PDGFR-alpha(Phospho Tyr849) Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated PDGFR-alpha in complex biological samples.

This antibody is supplied as a liquid formulation, ready to use for immediate application. It is provided in a convenient size and quantity, ensuring cost-effectiveness and minimizing wastage. The PDGFR-alpha(Phospho Tyr849) Polyclonal Antibody is compatible with a wide range of experimental conditions and can be used in both research and clinical settings.

In summary, the PDGFR-alpha(Phospho Tyr849) Polyclonal Antibody is a valuable tool for studying the phosphorylation status and functional regulation of PDGFR-alpha. Its high specificity, sensitivity, and versatility make it an essential component of any research or diagnostic laboratory working in the field of cellular signaling and molecular biology.