PCNA Polyclonal Antibody

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage| this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

The PCNA Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of proliferating cell nuclear antigen (PCNA) in various biological samples. PCNA is a key protein involved in DNA replication and repair, making it an essential marker for cell proliferation and DNA synthesis studies.

This polyclonal antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards PCNA. It has been extensively validated for use in various applications, including immunohistochemistry, western blotting, and flow cytometry.

The PCNA Polyclonal Antibody offers exceptional sensitivity, allowing for the detection of low levels of PCNA in even the most challenging samples. Its superior performance is attributed to its high signal-to-noise ratio and minimal background interference.

With its robust and reliable performance, this antibody is an indispensable tool for researchers and scientists working in the fields of cancer biology, cell biology, and molecular biology. It enables accurate and precise quantification of PCNA expression, facilitating a deeper understanding of cell proliferation and DNA replication processes.

Furthermore, the PCNA Polyclonal Antibody is provided in a convenient and user-friendly format, ensuring ease of use and compatibility with various experimental protocols. It is supplied in a liquid form, eliminating the need for reconstitution and minimizing the risk of sample contamination.

In summary, the PCNA Polyclonal Antibody is a highly specific, sensitive, and reliable tool for the detection and quantification of PCNA in various biological samples. Its exceptional performance and user-friendly format make it an ideal choice for researchers seeking accurate and reproducible results in their studies of cell proliferation and DNA synthesis.