PAK4(Phospho Ser474) Polyclonal Antibody

PAK proteins| a family of serine/threonine p21-activating kinases| include PAK1| PAK2| PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Introducing the PAK4(Phospho Ser474) Polyclonal Antibody, a highly specific and sensitive tool for the detection of PAK4 protein phosphorylated at Ser474. This antibody has been rigorously tested and validated for use in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The PAK4(Phospho Ser474) Polyclonal Antibody is produced using high-quality materials and advanced techniques, ensuring exceptional performance and reproducibility. It exhibits minimal cross-reactivity with non-phosphorylated PAK4 protein, making it an ideal choice for the specific detection of phosphorylated PAK4.

This antibody is suitable for use in a wide range of research areas, including cancer biology, cell signaling, and neurobiology. It is available in various sizes to meet the needs of different experimental setups.

In summary, the PAK4(Phospho Ser474) Polyclonal Antibody is a reliable and effective tool for the detection of phosphorylated PAK4 protein. Its high specificity and sensitivity make it an essential reagent for researchers studying PAK4 signaling pathways and related biological processes.