p38 Polyclonal Antibody

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals| and are involved in a wide variety of cellular processes such as proliferation| differentiation| transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs)| or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2| MEF2C| and MAX| cell cycle regulator CDC25B| and tumor suppressor p53| which suggest the roles of this kinase in stress related transcription and cell cycle regulation| as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encodingd

The p38 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of p38 protein expression in various biological samples. This antibody is produced using advanced immunization techniques and exhibits exceptional sensitivity and specificity towards p38, making it an ideal choice for researchers and scientists working in the field of cellular signaling pathways.

The p38 Polyclonal Antibody is designed to recognize and bind to the p38 protein, a member of the mitogen-activated protein kinase (MAPK) family. This protein plays a crucial role in cellular responses to various stress stimuli, including inflammation, oxidative stress, and DNA damage. By targeting p38, this antibody enables the investigation of its involvement in these signaling pathways and facilitates a deeper understanding of its functional significance.

This antibody is manufactured using high-quality materials and undergoes rigorous quality control measures to ensure its reliability and reproducibility. It has been extensively validated in a wide range of experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence. Its exceptional performance in these applications guarantees accurate and consistent results, allowing for confident data interpretation.

The p38 Polyclonal Antibody is supplied in a convenient and user-friendly format, ensuring ease of use and storage. It is provided as a liquid formulation, ready for immediate use without the need for additional reagents or preparations. Its long shelf life and stability make it a cost-effective choice for long-term experiments and repeated analyses.

In summary, the p38 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of p38 protein expression. Its exceptional sensitivity, specificity, and performance in various experimental techniques make it an invaluable asset for researchers and scientists studying cellular signaling pathways.