CCL22 Rabbit Polyclonal Antibody

May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes| dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils| eosinophils| and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69)| MDC(5-69) and MDC(7-69) seem not be active.|online information:CCL22 entry|PTM:The N-terminal processed forms MDC(3-69)| MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes.|Belongs to the intercrine beta (chemokine CC) family.|tissue specificity:Highly expressed in macrophage and in monocyte-derived dendritic cells| and thymus. Also found in lymph node| appendix| activated monocytes| resting and activated macrophages. Lower expression in lung and spleen. Very weak expression in small intestine. In lymph node expressed in a mature subset of Langerhans' cells (CD1a+ and CD83+). Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy. Expressed in atopic dermatitis| allergic contact dermatitis skin| and psoriasis| in both the eptdermis and dermis.|

The CCL22 Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of CCL22 protein in various biological samples. This antibody has been meticulously developed using advanced immunization techniques and exhibits exceptional affinity and selectivity towards CCL22.

With its superior performance, this antibody enables accurate and reliable analysis of CCL22 expression levels in research applications such as immunohistochemistry, western blotting, and enzyme-linked immunosorbent assays (ELISA). Its robustness and reproducibility make it an ideal choice for both qualitative and quantitative investigations.

The CCL22 Rabbit Polyclonal Antibody offers exceptional versatility, allowing for its utilization across a wide range of species, including human, mouse, and rat. Its broad reactivity ensures compatibility with diverse sample types, including tissue lysates, cell lysates, and serum.

Furthermore, this antibody has been rigorously validated to ensure consistent and reproducible results. Its high specificity minimizes the risk of cross-reactivity with other proteins, guaranteeing accurate and precise measurements of CCL22 levels.

In summary, the CCL22 Rabbit Polyclonal Antibody is a reliable and efficient tool for the detection and quantification of CCL22 protein. Its exceptional sensitivity, specificity, and versatility make it an invaluable asset for researchers in the field of immunology and related disciplines.