CCL22 Rabbit Polyclonal Antibody

May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes| dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils| eosinophils| and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69)| MDC(5-69) and MDC(7-69) seem not be active.|online information:CCL22 entry|PTM:The N-terminal processed forms MDC(3-69)| MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes.|Belongs to the intercrine beta (chemokine CC) family.|tissue specificity:Highly expressed in macrophage and in monocyte-derived dendritic cells| and thymus. Also found in lymph node| appendix| activated monocytes| resting and activated macrophages. Lower expression in lung and spleen. Very weak expression in small intestine. In lymph node expressed in a mature subset of Langerhans' cells (CD1a+ and CD83+). Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy. Expressed in atopic dermatitis| allergic contact dermatitis skin| and psoriasis| in both the eptdermis and dermis.|

The CCL22 Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of CCL22 protein in various biological samples. This antibody has been meticulously developed using advanced immunization techniques and exhibits exceptional affinity and selectivity towards CCL22.

With its superior performance characteristics, this antibody offers researchers a reliable and accurate means to investigate the expression and localization of CCL22 in a wide range of experimental settings. Its robustness and versatility make it an ideal choice for applications such as Western blotting, immunohistochemistry, and immunofluorescence.

The CCL22 Rabbit Polyclonal Antibody is manufactured under stringent quality control measures to ensure consistent and reproducible results. It has been extensively validated for its specificity, sensitivity, and reliability, guaranteeing optimal performance in experimental studies.

Furthermore, this antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. Its long shelf life ensures that researchers can confidently utilize this antibody for an extended period without compromising its performance.

In summary, the CCL22 Rabbit Polyclonal Antibody is a valuable tool for researchers seeking to explore the role and function of CCL22 in various biological processes. Its exceptional performance characteristics, stringent quality control, and user-friendly format make it an indispensable asset in the field of immunological research.