NFκB-p100(Phospho Ser869) Polyclonal Antibody

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas| some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.

The NFκB-p100(Phospho Ser869) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of NFκB-p100 protein phosphorylated at Ser869. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity for the target protein.

NFκB-p100 is a key regulator of various cellular processes, including inflammation, immune response, and cell survival. Phosphorylation of NFκB-p100 at Ser869 plays a crucial role in its activation and subsequent downstream signaling events. Therefore, the detection and analysis of phosphorylated NFκB-p100 are of great importance in understanding the molecular mechanisms underlying these processes.

The NFκB-p100(Phospho Ser869) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated NFκB-p100 in a wide range of sample types.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and quantity, ensuring cost-effectiveness and minimizing waste. The NFκB-p100(Phospho Ser869) Polyclonal Antibody is manufactured under strict quality control standards, guaranteeing consistent and reproducible results.

In summary, the NFκB-p100(Phospho Ser869) Polyclonal Antibody is a valuable tool for researchers studying NFκB signaling pathways and related cellular processes. Its high specificity, sensitivity, and versatility make it an essential component of any laboratory involved in molecular biology and biomedical research.