NF2(Phospho Ser10) Polyclonal Antibody

This gene encodes a protein that is similar to some members of the ERM (ezrin| radixin| moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins| proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults| significant expression is found in Schwann cells| meningeal cells| lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.

The NF2(Phospho Ser10) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of the phosphorylated form of the NF2 protein at Ser10 residue. This antibody has been meticulously developed and validated to ensure optimal performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The NF2 protein, also known as Merlin, plays a crucial role in cell growth regulation and tumor suppression. Phosphorylation of the NF2 protein at Ser10 residue has been implicated in various cellular processes, including cell cycle progression, cytoskeletal organization, and cell adhesion. Therefore, the ability to accurately detect and quantify the phosphorylated form of NF2 is of utmost importance in understanding its functional significance and its involvement in disease states.

Our NF2(Phospho Ser10) Polyclonal Antibody exhibits exceptional specificity and sensitivity, enabling reliable and reproducible results. It has been rigorously tested against a panel of cell lines and tissues to ensure minimal cross-reactivity with non-phosphorylated NF2 protein or other related proteins. This antibody demonstrates a high affinity for the phosphorylated form of NF2, allowing for precise detection even at low expression levels.

Furthermore, the NF2(Phospho Ser10) Polyclonal Antibody has been optimized for various experimental conditions, providing flexibility and versatility in its application. It exhibits excellent performance in both monoclonal and polyclonal antibody-based assays, making it an ideal choice for researchers in diverse fields, including cancer biology, cell signaling, and molecular biology.

In summary, the NF2(Phospho Ser10) Polyclonal Antibody is a reliable and efficient tool for the detection and analysis of the phosphorylated form of NF2 protein. Its exceptional specificity, sensitivity, and versatility make it an invaluable asset for researchers aiming to unravel the intricate mechanisms underlying NF2 protein function and its implications in various diseases.