Met(Phospho Tyr1356) Polyclonal Antibody

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide| which has been shown to reduce lung fibrosis. Binding of its ligand| hepatocyte growth factor| induces dimerization and activation of the receptor| which plays a role in cellular survival| embryogenesis| and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma| hepatocellular carcinoma| and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.

The Met(Phospho Tyr1356) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Met protein phosphorylated at tyrosine 1356. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

The Met protein, also known as hepatocyte growth factor receptor (HGFR), plays a crucial role in various cellular processes, including cell growth, survival, and migration. Phosphorylation of Met at tyrosine 1356 is a key event in the activation of downstream signaling pathways, leading to the regulation of cell proliferation and differentiation.

This polyclonal antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with other phosphorylated tyrosine residues, ensuring accurate and reliable results.

The Met(Phospho Tyr1356) Polyclonal Antibody is supplied as a liquid formulation, ready to use for immediate experimentation. It is provided in a convenient size and quantity, allowing for multiple experiments without the need for frequent reordering.

With its exceptional performance and reliability, the Met(Phospho Tyr1356) Polyclonal Antibody is an indispensable tool for researchers studying the role of Met protein phosphorylation in various biological processes. Its high specificity and sensitivity make it an ideal choice for both basic research and drug development studies.

Order your Met(Phospho Tyr1356) Polyclonal Antibody today and unlock new insights into the intricate mechanisms of Met protein signaling.