Lck(Phospho Tyr505) Polyclonal Antibody

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation| a PTK domain| and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs| respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles| and binds to cell surface receptors| including CD4 and CD8| and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described.

The Lck(Phospho Tyr505) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Lck protein phosphorylated at tyrosine 505. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity for the target protein.

Lck, also known as lymphocyte-specific protein tyrosine kinase, plays a crucial role in T-cell development and activation. Phosphorylation of Lck at tyrosine 505 is a key regulatory event that modulates its activity and downstream signaling pathways. The Lck(Phospho Tyr505) Polyclonal Antibody enables researchers to investigate the phosphorylation status of Lck and its functional implications in various cellular processes.

This antibody has been rigorously validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits exceptional sensitivity and specificity, allowing for accurate and reliable detection of phosphorylated Lck in complex biological samples.

The Lck(Phospho Tyr505) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is compatible with a wide range of experimental conditions and can be used in both basic research and clinical applications.

With its exceptional performance and reliability, the Lck(Phospho Tyr505) Polyclonal Antibody is an indispensable tool for researchers studying T-cell signaling pathways, immune responses, and related diseases. Its high specificity and sensitivity make it an ideal choice for investigating the role of Lck phosphorylation in various cellular processes.