Ku-70(Phospho Ser5) Polyclonal Antibody

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair| transposition| and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

The Ku-70(Phospho Ser5) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated serine 5 residues on the Ku-70 protein. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reliability.

The Ku-70 protein plays a crucial role in DNA repair and maintenance of genomic stability. Phosphorylation of serine 5 on Ku-70 has been implicated in various cellular processes, including DNA damage response and cell cycle regulation. Therefore, the ability to accurately detect and quantify this phosphorylation event is of great importance in understanding the underlying mechanisms of these processes.

The Ku-70(Phospho Ser5) Polyclonal Antibody exhibits exceptional specificity and sensitivity, enabling precise detection and quantification of phosphorylated serine 5 residues on the Ku-70 protein. It has been extensively validated in various experimental settings, including Western blotting, immunoprecipitation, and immunofluorescence.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy integration into existing laboratory protocols. The high affinity and selectivity of this antibody ensure reliable and reproducible results, making it an ideal choice for researchers and scientists working in the fields of DNA repair, genomics, and cell biology.

In summary, the Ku-70(Phospho Ser5) Polyclonal Antibody is a valuable tool for the detection and analysis of phosphorylated serine 5 residues on the Ku-70 protein. Its exceptional specificity, sensitivity, and reliability make it an essential component in studying the intricate mechanisms of DNA repair and cellular processes.