CARD11(Phospho-Ser652) Rabbit Polyclonal Antibody

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family| a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family| which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10| a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells| this protein activated NF-kappaB and induced the phosphorylation of BCL10.

The CARD11(Phospho-Ser652) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of CARD11 protein phosphorylated at Serine 652. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring excellent performance and reliability in various applications.

The CARD11 protein plays a crucial role in the regulation of immune responses and lymphocyte activation. Phosphorylation of Serine 652 has been identified as a key post-translational modification that modulates the activity of CARD11 and its downstream signaling pathways. Therefore, the detection and analysis of CARD11 phosphorylation at Serine 652 are of great importance in understanding the molecular mechanisms underlying immune responses and related diseases.

The CARD11(Phospho-Ser652) Rabbit Polyclonal Antibody exhibits exceptional specificity and sensitivity, enabling accurate and reliable detection of phosphorylated CARD11 at Serine 652. It has been extensively validated in various experimental settings, including Western blotting, immunoprecipitation, and immunofluorescence. This antibody demonstrates minimal cross-reactivity with non-phosphorylated CARD11 and other related proteins, ensuring reliable and specific results.

With its high affinity and excellent performance, the CARD11(Phospho-Ser652) Rabbit Polyclonal Antibody is an indispensable tool for researchers and scientists studying immune responses, lymphocyte activation, and related diseases. Its reliable and reproducible results make it an ideal choice for both basic research and clinical applications.

Order your CARD11(Phospho-Ser652) Rabbit Polyclonal Antibody today and unlock new insights into the intricate mechanisms of immune regulation and lymphocyte activation.