KCNQ2/3/4/5(Phospho Thr217/246/223/251) Polyclonal Antibody

The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability.  The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene| both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine| a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC)| also known as epilepsy| benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene.

The KCNQ2/3/4/5(Phospho Thr217/246/223/251) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated forms of KCNQ2, KCNQ3, KCNQ4, and KCNQ5 proteins. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

The KCNQ2/3/4/5(Phospho Thr217/246/223/251) Polyclonal Antibody is suitable for various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It recognizes the phosphorylated threonine residues at positions 217, 246, 223, and 251 of the KCNQ2, KCNQ3, KCNQ4, and KCNQ5 proteins, respectively. This antibody exhibits minimal cross-reactivity with non-phosphorylated forms of these proteins, ensuring accurate and specific detection.

With its high sensitivity and specificity, the KCNQ2/3/4/5(Phospho Thr217/246/223/251) Polyclonal Antibody is an invaluable tool for researchers studying the role of KCNQ2, KCNQ3, KCNQ4, and KCNQ5 proteins in various cellular processes and diseases. Its reliable performance and reproducibility make it an ideal choice for both basic research and clinical applications.

Order the KCNQ2/3/4/5(Phospho Thr217/246/223/251) Polyclonal Antibody today and unlock new insights into the phosphorylation status and function of KCNQ2, KCNQ3, KCNQ4, and KCNQ5 proteins.