JAK3(Phospho Tyr785) Polyclonal Antibody

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

The JAK3(Phospho Tyr785) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of JAK3 protein phosphorylated at tyrosine 785. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

JAK3, also known as Janus kinase 3, is a member of the Janus kinase family of intracellular non-receptor tyrosine kinases. It plays a crucial role in the signal transduction pathway mediated by cytokine receptors, particularly those involved in immune responses. Phosphorylation of JAK3 at tyrosine 785 is a key event in the activation of its kinase activity and subsequent downstream signaling.

The JAK3(Phospho Tyr785) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate detection and quantification of phosphorylated JAK3 protein in complex biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing wastage. The JAK3(Phospho Tyr785) Polyclonal Antibody is compatible with a wide range of experimental conditions and can be used in both research and clinical settings.

In summary, the JAK3(Phospho Tyr785) Polyclonal Antibody is a reliable and efficient tool for the study of JAK3 signaling pathways. Its high specificity and sensitivity make it an invaluable asset for researchers and clinicians working in the fields of immunology, oncology, and inflammation.