CaMKK2(Phospho-Ser511) Rabbit Polyclonal Antibody

The product of this gene belongs to the Serine/Threonine protein kinase family| and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory| neuronal differentiation and migration| neurite outgrowth| and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases.

The CaMKK2(Phospho-Ser511) Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of CaMKK2 protein phosphorylated at Serine 511. This antibody has been rigorously validated for its specificity and performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

CaMKK2 is a calcium/calmodulin-dependent protein kinase kinase that plays a crucial role in cellular signaling pathways. Phosphorylation of CaMKK2 at Serine 511 has been implicated in the regulation of its activity and downstream signaling events. Therefore, the ability to specifically detect and quantify this phosphorylation event is of utmost importance in understanding the functional implications of CaMKK2 in various biological processes.

The CaMKK2(Phospho-Ser511) Rabbit Polyclonal Antibody has been developed using high-quality rabbit polyclonal antibodies that have been raised against a synthetic peptide corresponding to the phosphorylated Serine 511 region of CaMKK2. This antibody exhibits excellent sensitivity and specificity, ensuring reliable and accurate results.

This antibody is supplied as a liquid formulation in a convenient size of 100 μg, allowing for multiple experiments and applications. It has been optimized for use in various experimental conditions and is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

In summary, the CaMKK2(Phospho-Ser511) Rabbit Polyclonal Antibody is a valuable tool for researchers studying the role of CaMKK2 phosphorylation in cellular signaling pathways. Its high specificity, sensitivity, and versatility make it an essential component of any study aiming to elucidate the functional implications of CaMKK2 in various biological processes.