IRS-1(phospho Tyr896) Polyclonal Antibody

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

The IRS-1(phospho Tyr896) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IRS-1 protein phosphorylated at tyrosine 896. This antibody has been meticulously developed and rigorously validated to ensure optimal performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The IRS-1 protein plays a crucial role in insulin signaling pathways, regulating glucose metabolism and cellular growth. Phosphorylation of IRS-1 at tyrosine 896 is a key event in the activation of downstream signaling cascades, making it an important target for research in the field of diabetes, obesity, and cancer.

Our IRS-1(phospho Tyr896) Polyclonal Antibody exhibits exceptional specificity, binding exclusively to the phosphorylated form of IRS-1 at tyrosine 896. This high specificity ensures accurate and reliable results, minimizing the risk of false positives or cross-reactivity with other proteins.

Furthermore, this antibody demonstrates outstanding sensitivity, enabling the detection of low levels of phosphorylated IRS-1 in complex biological samples. Its superior sensitivity allows for the detection of subtle changes in IRS-1 phosphorylation levels, facilitating the study of dynamic cellular processes and signaling events.

The IRS-1(phospho Tyr896) Polyclonal Antibody has been extensively validated using a variety of experimental approaches, including siRNA knockdown, peptide competition, and positive control validation. These rigorous validation procedures ensure the antibody's reliability and reproducibility, providing researchers with confidence in their experimental results.

In summary, the IRS-1(phospho Tyr896) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of phosphorylated IRS-1 at tyrosine 896. Its exceptional performance, combined with rigorous validation, makes it an invaluable asset for researchers studying insulin signaling pathways and related diseases.