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BT Lab

SKU:BT-AP01000

IRS-1(phospho Ser636) Polyclonal Antibody

IRS-1(phospho Ser636) Polyclonal Antibody

Regular price $275.00 USD
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This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

The IRS-1(phospho Ser636) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of IRS-1 protein phosphorylated at Serine 636. This antibody has been meticulously developed and rigorously validated to ensure optimal performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The IRS-1 protein plays a crucial role in insulin signaling pathways and is involved in regulating glucose metabolism and cellular growth. Phosphorylation of IRS-1 at Serine 636 has been implicated in the modulation of insulin sensitivity and the development of insulin resistance. Therefore, the IRS-1(phospho Ser636) Polyclonal Antibody serves as an invaluable tool for researchers studying the intricate mechanisms underlying insulin signaling and its dysregulation in various metabolic disorders.

This antibody exhibits exceptional specificity, displaying minimal cross-reactivity with non-phosphorylated IRS-1 or other phosphorylation sites. Its high sensitivity allows for the detection of low levels of phosphorylated IRS-1, enabling accurate quantification and analysis of protein expression levels in complex biological samples.

The IRS-1(phospho Ser636) Polyclonal Antibody has been extensively validated using a variety of experimental approaches, ensuring reliable and reproducible results. Its superior performance is further enhanced by its compatibility with multiple detection methods, facilitating flexibility and versatility in experimental design.

With its exceptional specificity, sensitivity, and reliability, the IRS-1(phospho Ser636) Polyclonal Antibody is an indispensable tool for researchers investigating the intricate molecular mechanisms underlying insulin signaling and its dysregulation in metabolic disorders.

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