C1S (light chain| Cleaved-Ile438) Rabbit Polyclonal Antibody

Catalytic activity:Cleavage of Arg-|-Ala bond in complement component C4 to form C4a and C4b| and Lys(or Arg)-|-Lys bond in complement component C2 to form C2a and C2b: the 'classical' pathway C3 convertase.|disease:Defects in C1S are the cause of selective C1s deficiency

The C1S (light chain| Cleaved-Ile438) Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of C1S protein in various biological samples. This antibody has been developed using advanced immunization techniques and exhibits exceptional sensitivity and specificity towards the target protein.

The C1S protein plays a crucial role in the complement system, which is an essential component of the immune response. It is involved in the activation of the classical pathway of the complement system, leading to the elimination of pathogens and the initiation of an inflammatory response. The cleavage of Ile438 in the light chain of C1S is a critical event in the activation of this protein.

This rabbit polyclonal antibody has been carefully designed to specifically recognize the cleaved form of C1S at Ile438. It has been extensively validated using various experimental approaches, including Western blotting, immunohistochemistry, and immunofluorescence. The antibody exhibits high affinity and selectivity towards the cleaved form of C1S, ensuring accurate and reliable detection.

The C1S (light chain| Cleaved-Ile438) Rabbit Polyclonal Antibody is supplied as a purified and concentrated solution, ensuring optimal performance and ease of use. It is suitable for a wide range of applications, including protein expression analysis, biomarker discovery, and disease research. The antibody is compatible with various detection methods and can be used in both qualitative and quantitative assays.

In summary, the C1S (light chain| Cleaved-Ile438) Rabbit Polyclonal Antibody is a valuable tool for researchers studying the complement system and its role in immune responses. Its high specificity, sensitivity, and reliability make it an ideal choice for accurate detection and analysis of C1S protein in various biological samples.