c-Myb (Acetyl Lys480) Rabbit Polyclonal Antibody

Comprised of 3 domains; an N-terminal DNA-binding domain| a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression.|Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC

Introducing the c-Myb (Acetyl Lys480) Rabbit Polyclonal Antibody, a highly specific and sensitive tool for the detection of c-Myb protein in various biological samples. This antibody is produced using high-quality rabbit polyclonal antibodies that have been raised against the acetylated lysine 480 residue of the c-Myb protein. The acetylation of lysine 480 is a critical post-translational modification that regulates the activity of c-Myb, a transcription factor that plays a crucial role in the regulation of cell proliferation, differentiation, and apoptosis.

The c-Myb (Acetyl Lys480) Rabbit Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunoprecipitation, and immunohistochemistry. It recognizes the acetylated form of c-Myb protein with high affinity and specificity, and does not cross-react with other proteins or acetylated lysine residues.

This antibody is supplied as a purified IgG fraction, and is suitable for use in both research and diagnostic applications. It is provided in a convenient format, with a concentration of 1 mg/ml, and can be used at a dilution of 1:1000 for Western blotting and immunoprecipitation, and 1:200 for immunohistochemistry.

In summary, the c-Myb (Acetyl Lys480) Rabbit Polyclonal Antibody is a reliable and sensitive tool for the detection of acetylated c-Myb protein in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers and clinicians studying the role of c-Myb in various cellular processes and diseases.