HIRA(Phospho Thr555) Polyclonal Antibody

This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast| flies| and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome| and insufficient production of the gene may disrupt normal embryonic development.

The HIRA(Phospho Thr555) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of HIRA protein phosphorylated at threonine 555. This antibody is produced using advanced techniques to ensure high affinity and specificity, making it an ideal choice for various applications in research and diagnostics.

The HIRA protein plays a crucial role in chromatin remodeling and transcriptional regulation, making it a key target for studying cellular processes such as DNA repair, cell cycle progression, and gene expression. The phosphorylation of HIRA at threonine 555 has been implicated in the regulation of its activity and function, making it an important site of investigation.

This polyclonal antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with other proteins, ensuring accurate and reliable results.

The HIRA(Phospho Thr555) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy customization and optimization in different experimental setups. The antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

With its exceptional performance and reliability, the HIRA(Phospho Thr555) Polyclonal Antibody is an indispensable tool for researchers and clinicians working in the fields of molecular biology, genetics, and cancer research. Its ability to specifically detect and quantify phosphorylated HIRA protein at threonine 555 opens up new avenues for understanding the intricate mechanisms underlying cellular processes and disease pathogenesis.