HDAC3(Phospho Ser424) Polyclonal Antibody

Histones play a critical role in transcriptional regulation| cell cycle progression| and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

The HDAC3(Phospho Ser424) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of HDAC3 protein phosphorylated at Serine 424. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

HDAC3, also known as Histone Deacetylase 3, is a key enzyme involved in the regulation of gene expression through the modification of histone proteins. Phosphorylation of HDAC3 at Serine 424 has been shown to play a crucial role in its activity and function.

This polyclonal antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of HDAC3 phosphorylated at Serine 424 in various biological samples.

The HDAC3(Phospho Ser424) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing waste. The antibody is also compatible with a wide range of secondary detection systems, allowing for flexibility in experimental design.

Researchers and scientists in the fields of molecular biology, biochemistry, and cell biology will greatly benefit from the use of this high-quality antibody. Its reliable performance and specificity make it an indispensable tool for studying the role of HDAC3 phosphorylation in various cellular processes and disease mechanisms.

In summary, the HDAC3(Phospho Ser424) Polyclonal Antibody is a valuable research tool that offers exceptional sensitivity and specificity for the detection and quantification of HDAC3 protein phosphorylated at Serine 424. Its reliable performance and compatibility with various applications make it an essential component in any laboratory studying HDAC3 and its associated biological processes.