GSK3 alpha/beta(Phospho Tyr279/216) Polyclonal Antibody

This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase| and transcription factors| such as JUN. It also plays a role in the WNT and PI3K signaling pathways| as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease.

The GSK3 alpha/beta(Phospho Tyr279/216) Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of GSK3 alpha and beta isoforms. This antibody has been developed using advanced techniques to ensure exceptional sensitivity and specificity.

GSK3 alpha and beta are serine/threonine kinases that play crucial roles in various cellular processes, including cell proliferation, differentiation, and apoptosis. Dysregulation of GSK3 activity has been implicated in the pathogenesis of numerous diseases, including cancer, diabetes, and neurodegenerative disorders.

This polyclonal antibody has been raised against a synthetic peptide corresponding to the phosphorylated tyrosine residues at positions 279 and 216 of GSK3 alpha and beta isoforms. It has been extensively validated for its ability to specifically recognize the phosphorylated form of GSK3 alpha and beta in various experimental settings, including Western blotting, immunoprecipitation, and immunofluorescence.

The GSK3 alpha/beta(Phospho Tyr279/216) Polyclonal Antibody exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of GSK3 alpha and beta isoforms in complex biological samples. It is suitable for use in both basic research and clinical applications.

With its high-quality performance and robustness, this antibody is an indispensable tool for researchers and clinicians studying the role of GSK3 alpha and beta in various physiological and pathological processes.