GRB10(Phospho Tyr67) Polyclonal Antibody

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner| with expression observed from the paternal allele in the brain| and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified.

The GRB10(Phospho Tyr67) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of GRB10 protein phosphorylated at tyrosine 67. This antibody is produced using state-of-the-art techniques and exhibits exceptional performance in various applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

GRB10 is a crucial adaptor protein involved in multiple cellular signaling pathways, particularly those mediated by receptor tyrosine kinases. Phosphorylation of GRB10 at tyrosine 67 has been implicated in the regulation of insulin signaling, growth factor signaling, and cellular proliferation. Therefore, the ability to accurately measure the phosphorylation status of GRB10 at this specific site is of great importance in understanding the underlying mechanisms of various physiological and pathological processes.

The GRB10(Phospho Tyr67) Polyclonal Antibody demonstrates exceptional specificity, exhibiting minimal cross-reactivity with non-phosphorylated GRB10 or other related proteins. This ensures reliable and accurate results, allowing for precise quantification of phosphorylated GRB10 levels in complex biological samples.

Furthermore, this antibody exhibits high sensitivity, enabling the detection of low abundance phosphorylated GRB10 even in limited sample quantities. Its robust performance and reproducibility make it an ideal choice for both qualitative and quantitative analysis of GRB10 phosphorylation.

The GRB10(Phospho Tyr67) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, allowing for easy integration into existing laboratory protocols.

In summary, the GRB10(Phospho Tyr67) Polyclonal Antibody is a reliable and efficient tool for the detection and quantification of phosphorylated GRB10 at tyrosine 67. Its exceptional specificity, sensitivity, and ease of use make it an invaluable asset for researchers studying cellular signaling pathways and their implications in various biological processes.