GR(Phospho Ser211) Polyclonal Antibody

This gene encodes glucocorticoid receptor| which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription| and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm| but upon ligand binding| is transported into the nucleus. It is involved in inflammatory responses| cellular proliferation| and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described| and shown to be functional| displaying diverse cytoplasm-to-nucleus trafficking pat

The GR(Phospho Ser211) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of the phosphorylated form of the glucocorticoid receptor (GR) at serine 211 residue. This antibody has been meticulously developed and rigorously validated to ensure optimal performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The GR(Phospho Ser211) Polyclonal Antibody exhibits exceptional affinity and selectivity towards the phosphorylated serine 211 residue of the GR protein. It has been extensively tested and validated using a variety of cell lines and tissues, ensuring reliable and reproducible results. This antibody demonstrates minimal cross-reactivity with non-phosphorylated forms of the GR protein, further enhancing its specificity.

With its high sensitivity, this antibody allows for the detection of even low levels of phosphorylated GR at serine 211, enabling accurate quantification and analysis. Its robust performance and consistent results make it an invaluable tool for researchers studying the role of GR phosphorylation in various biological processes, including stress response, inflammation, and metabolism.

The GR(Phospho Ser211) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It has been optimized for ease of use and compatibility with commonly used experimental protocols. Its long shelf life and stability ensure reliable performance over an extended period, minimizing the need for frequent antibody replacements.

In summary, the GR(Phospho Ser211) Polyclonal Antibody is a highly reliable and specific tool for the detection and quantification of phosphorylated GR at serine 211. Its exceptional sensitivity, selectivity, and compatibility with various applications make it an essential asset for researchers in the field of glucocorticoid receptor signaling and related studies.