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SKU:BT-AP00772

GFAP(Phospho Ser38) Polyclonal Antibody

GFAP(Phospho Ser38) Polyclonal Antibody

Regular price $275.00 USD
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This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease| a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

The GFAP(Phospho Ser38) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of GFAP protein phosphorylated at Serine 38. This antibody is produced using a polyclonal approach, ensuring a diverse range of epitope recognition and enhanced sensitivity.

GFAP, or Glial Fibrillary Acidic Protein, is an intermediate filament protein predominantly expressed in astrocytes, a type of glial cell in the central nervous system. Phosphorylation of GFAP at Serine 38 has been implicated in various cellular processes, including astrocyte activation and cytoskeletal remodeling.

The GFAP(Phospho Ser38) Polyclonal Antibody has been rigorously validated for its specificity and sensitivity through various experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated GFAP and other related proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, ready for immediate use in various applications. It is recommended for use in research studies investigating the role of GFAP phosphorylation in neurological disorders, brain injury, and neurodegenerative diseases.

With its high specificity, sensitivity, and versatility, the GFAP(Phospho Ser38) Polyclonal Antibody is an indispensable tool for researchers and scientists in the field of neuroscience and cellular biology.

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