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SKU:BT-AP06303

Bcl-6 (Acetyl Lys379) Rabbit Polyclonal Antibody

Bcl-6 (Acetyl Lys379) Rabbit Polyclonal Antibody

Regular price $275.00 USD
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disease:A chromosomal aberration involving BCL6 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with POU2AF1/OBF1.|disease:A chromosomal aberration involving BCL6 may be a cause of lymphoma. Translocation t(3;4)(q27;p11) with ARHH/TTF.|disease:Chromosomal aberrations involving BCL6 may be a cause of B-cell non-Hodgkin lymphoma. Translocation t(3;14)(q27;q32); translocation t(3;22)(q27;q11) with immunoglobulin gene regions.|Transcriptional repressor which is required for germinal center formation and antibody affinity maturation. Probably plays an important role in lymphomagenesis.|induction:Down-regulated during maturation of dendritic cells by selective stimuli such as LPS| CD40L and zymosan.|PTM:Phosphorylated by MAPK1 in response to antigen receptor activation. Phosphorylation induces its degradation by ubiquitin/proteasome pathway.|Contains 1 BTB (POZ) domain.|Contains 6 C2H2-type zinc fingers.|subunit:Interacts with ZBTB7 and BCL6B (By similarity). Interacts with the catalytic domain of HDAC9.|tissue specificity:Expressed in germinal center T and B cells and in primary immature dendritic cells.|

Introducing the Bcl-6 (Acetyl Lys379) Rabbit Polyclonal Antibody, a highly reliable and efficient tool for the detection and analysis of Bcl-6 protein expression. This antibody is specifically designed to target the acetylated lysine residue at position 379 of the Bcl-6 protein, ensuring accurate and precise results.

The Bcl-6 (Acetyl Lys379) Rabbit Polyclonal Antibody exhibits exceptional sensitivity and specificity, making it an ideal choice for various applications, including immunohistochemistry, western blotting, and immunofluorescence. Its robust performance guarantees reliable and reproducible data, enabling researchers to confidently investigate the role of Bcl-6 in various biological processes.

Crafted with utmost precision and utilizing advanced technology, this antibody offers unparalleled performance in terms of signal intensity and signal-to-noise ratio. Its high affinity for the acetylated lysine residue at position 379 of Bcl-6 ensures minimal cross-reactivity, resulting in accurate and specific detection.

Furthermore, the Bcl-6 (Acetyl Lys379) Rabbit Polyclonal Antibody is manufactured under stringent quality control measures, ensuring batch-to-batch consistency and reliability. Each lot is thoroughly tested to meet the highest standards of quality, guaranteeing optimal performance and reproducibility.

In summary, the Bcl-6 (Acetyl Lys379) Rabbit Polyclonal Antibody is a superior tool for the detection and analysis of Bcl-6 protein expression. Its exceptional sensitivity, specificity, and reliability make it an indispensable asset for researchers in the field of molecular biology, immunology, and cancer research. Trust in the Bcl-6 (Acetyl Lys379) Rabbit Polyclonal Antibody to deliver accurate and precise results, enabling groundbreaking discoveries in the realm of Bcl-6 biology.

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