Gab 2(Phospho Tyr643) Polyclonal Antibody

This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain| and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors| and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

The Gab 2(Phospho Tyr643) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of Gab 2 protein phosphorylated at tyrosine 643. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

The Gab 2 protein plays a crucial role in various cellular processes, including cell growth, differentiation, and survival. Phosphorylation of Gab 2 at tyrosine 643 is known to be involved in the activation of downstream signaling pathways, making it an important target for research in the field of signal transduction.

The Gab 2(Phospho Tyr643) Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various experimental settings, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated Gab 2 protein, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is recommended for use in a wide range of applications, including basic research, drug discovery, and diagnostic development.

In summary, the Gab 2(Phospho Tyr643) Polyclonal Antibody is a valuable tool for researchers studying the role of Gab 2 protein phosphorylation in cellular signaling pathways. Its high specificity, sensitivity, and reliability make it an essential component of any laboratory focused on signal transduction research.