BAP1(Phospho-Ser592) Rabbit Polyclonal Antibody

This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition| the enzyme may be involved in regulation of transcription| regulation of cell cycle and growth| response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS)| which involves increased risk of cancers including malignant mesothelioma| uveal melanoma and cutaneous melanoma.

The BAP1(Phospho-Ser592) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of BAP1 protein phosphorylated at serine 592. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring excellent performance and reliability in various applications.

The BAP1 protein plays a crucial role in cellular processes such as DNA repair, cell cycle regulation, and tumor suppression. Phosphorylation of BAP1 at serine 592 has been implicated in the modulation of its enzymatic activity and protein-protein interactions. Therefore, the BAP1(Phospho-Ser592) Rabbit Polyclonal Antibody serves as an invaluable tool for studying the functional significance of BAP1 phosphorylation in various biological contexts.

This antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with other phosphorylated proteins, ensuring accurate and reliable results.

The BAP1(Phospho-Ser592) Rabbit Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size of 100 μg, allowing for multiple experiments without the need for frequent reordering. The antibody is stored at -20°C, ensuring long-term stability and preserving its functionality.

In summary, the BAP1(Phospho-Ser592) Rabbit Polyclonal Antibody is a highly specific and sensitive tool that enables researchers to investigate the role of BAP1 phosphorylation in various biological processes. Its excellent performance, reliability, and ease of use make it an essential component in any laboratory studying BAP1 protein function.