Flt-1(Phospho Tyr1333) Polyclonal Antibody

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains| a transmembrane segment| and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A| VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells| placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened| soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

The Flt-1(Phospho Tyr1333) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Flt-1 protein phosphorylated at Tyr1333. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

Flt-1, also known as vascular endothelial growth factor receptor 1 (VEGFR-1), plays a crucial role in angiogenesis and vascular development. Phosphorylation of Flt-1 at Tyr1333 has been implicated in various physiological and pathological processes, including tumor growth, metastasis, and inflammation.

The Flt-1(Phospho Tyr1333) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated Flt-1 in complex biological samples.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effectiveness and minimizing waste. The Flt-1(Phospho Tyr1333) Polyclonal Antibody is manufactured under strict quality control standards, ensuring consistent and reproducible results.

In summary, the Flt-1(Phospho Tyr1333) Polyclonal Antibody is a valuable tool for researchers studying the role of Flt-1 phosphorylation in various biological processes. Its high specificity, sensitivity, and reliability make it an essential component of any study involving Flt-1 signaling pathways.