Flt-1(Phospho Tyr1048) Polyclonal Antibody

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains| a transmembrane segment| and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A| VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells| placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened| soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

The Flt-1(Phospho Tyr1048) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Flt-1 protein phosphorylated at Tyr1048 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

Flt-1, also known as VEGFR-1, is a receptor tyrosine kinase that plays a crucial role in angiogenesis and vascular development. Phosphorylation of the Tyr1048 residue in Flt-1 is known to regulate its signaling pathway and downstream cellular responses. Therefore, the Flt-1(Phospho Tyr1048) Polyclonal Antibody serves as an invaluable tool for researchers studying the molecular mechanisms underlying angiogenesis and vascular biology.

This antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated Flt-1 protein in complex biological samples.

The Flt-1(Phospho Tyr1048) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage. The antibody is manufactured under strict quality control standards, guaranteeing consistent and reproducible results.

In summary, the Flt-1(Phospho Tyr1048) Polyclonal Antibody is a highly reliable and efficient tool for researchers investigating the role of Flt-1 phosphorylation in angiogenesis and vascular development. Its exceptional sensitivity and specificity make it an indispensable asset in the field of molecular biology and biomedical research.