BT Lab
SKU:BT-AP06261
Flg(Phospho Tyr654) Polyclonal Antibody
Flg(Phospho Tyr654) Polyclonal Antibody
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The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family| where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region| composed of three immunoglobulin-like domains| a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors| setting in motion a cascade of downstream signals| ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome| Jackson-Weiss syndrome|
The Flg(Phospho Tyr654) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated tyrosine 654 in the Flg protein. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.
The Flg protein plays a crucial role in various cellular processes, including cell signaling, proliferation, and differentiation. Phosphorylation of tyrosine residues in the Flg protein is known to regulate its function and activity. Therefore, the ability to accurately detect and quantify phosphorylated tyrosine 654 in the Flg protein is essential for understanding its role in cellular processes and disease mechanisms.
The Flg(Phospho Tyr654) Polyclonal Antibody exhibits exceptional specificity and sensitivity, enabling precise detection and quantification of phosphorylated tyrosine 654 in the Flg protein. It has been extensively validated through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence.
This antibody is supplied as a liquid formulation, allowing for easy handling and convenient use in a wide range of applications. It is suitable for both research and diagnostic purposes, making it an invaluable tool for scientists and clinicians alike.
In summary, the Flg(Phospho Tyr654) Polyclonal Antibody is a reliable and high-performance reagent that enables accurate detection and analysis of phosphorylated tyrosine 654 in the Flg protein. Its exceptional specificity and sensitivity, along with its versatility in various experimental techniques, make it an essential tool for studying the role of Flg protein in cellular processes and disease mechanisms.
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