FGFR1 Polyclonal Antibody

The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family| where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region| composed of three immunoglobulin-like domains| a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors| setting in motion a cascade of downstream signals| ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome| Jackson-Weiss syndrome|

The FGFR1 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of FGFR1 protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring high quality and reliability in experimental results.

The FGFR1 Polyclonal Antibody exhibits exceptional affinity and specificity towards FGFR1, a receptor tyrosine kinase involved in various cellular processes, including cell proliferation, differentiation, and survival. It recognizes both the full-length and cleaved forms of FGFR1, enabling comprehensive analysis of its expression and activation status.

This antibody is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated in various cell lines and tissues, demonstrating robust and consistent performance. Its superior sensitivity allows for the detection of low levels of FGFR1 expression, making it an ideal choice for both basic research and clinical studies.

The FGFR1 Polyclonal Antibody is provided in a convenient and ready-to-use format, ensuring ease of use and minimal preparation time. It is supplied in a liquid form, allowing for direct application without the need for reconstitution. The antibody is also available in different sizes to accommodate various experimental needs.

With its exceptional specificity, sensitivity, and reliability, the FGFR1 Polyclonal Antibody is an indispensable tool for researchers and clinicians studying FGFR1 biology and its implications in various diseases, including cancer and developmental disorders. Trust in its performance to unlock new insights and advance scientific understanding in the field.