FGFR-4(Phospho Tyr642) Polyclonal Antibody

The protein encoded by this gene is a member of the fibroblast growth factor receptor family| where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region| composed of three immunoglobulin-like domains| a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors| setting in motion a cascade of downstream signals| ultimately influencing mitogenesis and differentiation. The genomic organization of this gene| compared to members 1-3| encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed| there is no evidence that the C-terminal half of the IgII

The FGFR-4(Phospho Tyr642) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of FGFR-4 protein phosphorylated at tyrosine 642 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

The FGFR-4 protein plays a crucial role in various cellular processes, including cell growth, differentiation, and survival. Phosphorylation of tyrosine 642 residue is known to regulate the activation and signaling of FGFR-4, making it an important target for research in the field of cell signaling and cancer biology.

This polyclonal antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of FGFR-4 phosphorylated at tyrosine 642 residue in various sample types.

The FGFR-4(Phospho Tyr642) Polyclonal Antibody is supplied as a liquid formulation, ready to use for immediate application. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage. The antibody is also available in different quantities to meet the specific needs of researchers and laboratories.

With its exceptional performance and reliability, the FGFR-4(Phospho Tyr642) Polyclonal Antibody is an indispensable tool for scientists and researchers involved in the study of FGFR-4 signaling pathways and its implications in various diseases, particularly cancer. Its high specificity and sensitivity make it an ideal choice for accurate and precise detection of FGFR-4 phosphorylation, facilitating a deeper understanding of cellular processes and potential therapeutic targets.