ATM(Phospho Ser1987) Rabbit Polyclonal Antibody

The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus| it functions as a regulator of a wide variety of downstream proteins| including tumor suppressor proteins p53 and BRCA1| checkpoint kinase CHK2| checkpoint proteins RAD17 and RAD9| and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia| an autosomal recessive disorder.

The ATM(Phospho Ser1987) Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of ATM protein phosphorylated at Ser1987. This antibody is produced using high-quality rabbit polyclonal antibodies that have been purified and validated for use in a variety of applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

The ATM protein is a key regulator of the DNA damage response pathway, and phosphorylation of Ser1987 is a critical event in the activation of ATM in response to DNA damage. The ATM(Phospho Ser1987) Rabbit Polyclonal Antibody is therefore an essential tool for researchers studying the DNA damage response pathway and its role in cancer and other diseases.

This antibody has been rigorously tested for specificity and sensitivity, ensuring that it provides reliable and reproducible results in a range of experimental conditions. It is supplied in a convenient format, with sufficient antibody for multiple experiments, and is compatible with a range of detection methods and secondary antibodies.

Overall, the ATM(Phospho Ser1987) Rabbit Polyclonal Antibody is a high-quality research tool that is essential for researchers studying the DNA damage response pathway and its role in disease. Its high specificity and sensitivity make it an ideal choice for a range of applications, and its convenient format and compatibility with a range of detection methods make it a versatile and valuable addition to any research laboratory.