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SKU:BT-AP00661

FAK(Phospho Tyr397) Polyclonal Antibody

FAK(Phospho Tyr397) Polyclonal Antibody

Regular price $275.00 USD
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This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene| but the full-length natures of only four of them have been determined.

The FAK (Phospho Tyr397) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of focal adhesion kinase (FAK) phosphorylated at tyrosine 397. FAK is a crucial protein involved in various cellular processes, including cell adhesion, migration, and proliferation. The phosphorylation of FAK at tyrosine 397 is a key event in the activation of FAK and subsequent downstream signaling pathways.

This polyclonal antibody has been meticulously developed and rigorously validated to ensure its exceptional performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) applications. It exhibits a high affinity and specificity towards the phosphorylated form of FAK at tyrosine 397, enabling accurate and reliable detection of this critical post-translational modification.

The FAK (Phospho Tyr397) Polyclonal Antibody offers numerous advantages, including its versatility in various experimental settings and compatibility with multiple sample types, such as cell lysates, tissue sections, and cultured cells. Its exceptional sensitivity allows for the detection of low-abundance phosphorylated FAK, even in complex biological samples.

Furthermore, this antibody has been extensively characterized to ensure minimal cross-reactivity with non-phosphorylated FAK and other related proteins, thereby enhancing the specificity of the detection. Its robust performance and reproducibility make it an ideal choice for researchers and scientists working in the fields of cell biology, cancer research, and signal transduction.

In summary, the FAK (Phospho Tyr397) Polyclonal Antibody is a reliable and efficient tool for the detection and analysis of phosphorylated FAK at tyrosine 397. Its exceptional sensitivity, specificity, and versatility make it an invaluable asset for researchers aiming to unravel the intricate mechanisms underlying FAK signaling pathways and their implications in various physiological and pathological processes.

The FAK (Phospho Tyr397) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of focal adhesion kinase (FAK) phosphorylated at tyrosine 397. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

FAK is a crucial protein involved in various cellular processes, including cell adhesion, migration, and proliferation. Phosphorylation of FAK at tyrosine 397 is a key event in the activation of FAK and subsequent downstream signaling pathways. Therefore, the detection and quantification of phosphorylated FAK at this site are of great importance in understanding cellular signaling and its implications in various physiological and pathological conditions.

The FAK (Phospho Tyr397) Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated FAK at tyrosine 397. It has been extensively validated for use in various applications, including Western blotting, immunoprecipitation, immunofluorescence, and immunohistochemistry.

This antibody is manufactured under stringent quality control measures, ensuring consistent performance and reproducibility. It is supplied as a liquid formulation, ready for immediate use, and is compatible with a wide range of experimental conditions and sample types.

In summary, the FAK (Phospho Tyr397) Polyclonal Antibody is a valuable tool for researchers and scientists studying FAK signaling pathways and its role in cellular processes. Its high specificity, sensitivity, and versatility make it an ideal choice for various applications, facilitating accurate and reliable analysis of phosphorylated FAK at tyrosine 397.

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