FADD(Phospho Ser191) Polyclonal Antibody

The Fas associated via death domain encoded by FADD is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain| this protein can be recruited by TNFRSF6/Fas-receptor| tumor necrosis factor receptor| TNFRSF25| and TNFSF10/TRAIL-receptor| and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein| which allows it to recruit caspase-8| and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.

The FADD (Phospho Ser191) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of FADD protein phosphorylated at Ser191. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

The FADD protein plays a crucial role in the regulation of apoptosis, a process essential for maintaining tissue homeostasis and eliminating damaged cells. Phosphorylation of FADD at Ser191 has been implicated in the modulation of its function and downstream signaling pathways.

This polyclonal antibody has been extensively validated for its specificity and sensitivity in various experimental settings, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated FADD and other related proteins, ensuring accurate and reliable results.

The FADD (Phospho Ser191) Polyclonal Antibody is supplied as a liquid formulation in a convenient size, allowing for easy handling and storage. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps.

With its exceptional performance and reliability, the FADD (Phospho Ser191) Polyclonal Antibody is an indispensable tool for researchers studying apoptosis and its regulatory mechanisms. Its high specificity and sensitivity make it an ideal choice for both basic research and clinical applications.

Order your FADD (Phospho Ser191) Polyclonal Antibody today and unlock new insights into the intricate world of apoptosis regulation.