ER beta(Phospho Ser105) Polyclonal Antibody

This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus| cytoplasm| and mitochondria. Upon binding to 17beta-estradiol or related ligands| the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described| but the full-length nature of some of these variants has not been fully characterized.

The ER beta(Phospho Ser105) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated Ser105 residues on the ER beta protein. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target epitope.

The ER beta protein plays a crucial role in various cellular processes, including gene transcription, cell proliferation, and differentiation. Phosphorylation of Ser105 on the ER beta protein has been implicated in the regulation of its activity and function. Therefore, the ER beta(Phospho Ser105) Polyclonal Antibody serves as an invaluable tool for researchers studying the intricate mechanisms underlying ER beta signaling pathways.

This antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunoprecipitation, and immunofluorescence. Its high sensitivity allows for the detection of even low levels of phosphorylated ER beta protein, enabling accurate and reliable quantification of phosphorylation events.

The ER beta(Phospho Ser105) Polyclonal Antibody is manufactured under stringent quality control standards, ensuring batch-to-batch consistency and reproducibility. It is supplied as a liquid formulation, ready for immediate use, and is compatible with various sample types, including cell lysates and tissue extracts.

In summary, the ER beta(Phospho Ser105) Polyclonal Antibody is a superior research tool that enables the investigation of ER beta phosphorylation events with exceptional sensitivity and specificity. Its versatility and reliability make it an indispensable asset for scientists and researchers in the field of cellular signaling and hormone receptor biology.