eNOS(Phospho-Ser1179) Polyclonal Antibody

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes| including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene.

The eNOS(Phospho-Ser1179) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated endothelial nitric oxide synthase (eNOS) at serine 1179 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

Endothelial nitric oxide synthase (eNOS) is a key enzyme involved in the production of nitric oxide (NO), a critical signaling molecule in various physiological and pathological processes. Phosphorylation of eNOS at serine 1179 residue is known to enhance its enzymatic activity, leading to increased NO production and subsequent regulation of vascular tone, blood pressure, and endothelial function.

The eNOS(Phospho-Ser1179) Polyclonal Antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated eNOS and other related proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, ready for immediate use in various research applications. It is recommended for use in both in vitro and in vivo studies, enabling researchers to investigate the phosphorylation status of eNOS at serine 1179 residue in different biological samples and experimental models.

With its exceptional performance and reliability, the eNOS(Phospho-Ser1179) Polyclonal Antibody is an indispensable tool for researchers studying the role of eNOS phosphorylation in cardiovascular physiology, endothelial dysfunction, and related diseases. Its high specificity and sensitivity make it an ideal choice for both basic research and drug development studies targeting the eNOS signaling pathway.