E-cadherin Polyclonal Antibody

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants| at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats| a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric| breast| colorectal| thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation| invasion| and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.

The E-Cadherin Polyclonal Antibody is a highly reliable and efficient tool designed for the detection and analysis of E-Cadherin protein expression in various biological samples. This antibody is produced using advanced techniques, ensuring exceptional specificity and sensitivity.

With its polyclonal nature, this antibody exhibits a broad reactivity, making it suitable for a wide range of applications, including immunohistochemistry, western blotting, and immunofluorescence. It has been extensively validated and proven to deliver consistent and accurate results across different experimental conditions.

The E-Cadherin Polyclonal Antibody offers exceptional performance in identifying E-Cadherin, a crucial protein involved in cell adhesion and tissue integrity. Its high affinity and selectivity enable precise detection and quantification of E-Cadherin expression levels, facilitating comprehensive research in various fields, such as cancer biology, developmental biology, and cell signaling.

This antibody is supplied in a convenient format, ensuring ease of use and storage. It is provided in a liquid form, ready for immediate application, eliminating the need for time-consuming reconstitution. Additionally, it is stable and long-lasting, maintaining its functionality even after prolonged storage.

Choose the E-Cadherin Polyclonal Antibody for its exceptional quality, reliability, and versatility. It is an indispensable tool for researchers and scientists seeking to unravel the intricate mechanisms underlying cellular processes and diseases.