APP(Phospho-Thr668) Rabbit Polyclonal Antibody

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation| while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition| two of the peptides are antimicrobial peptides| having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

The APP(Phospho-Thr668) Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of Amyloid Precursor Protein (APP) phosphorylated at threonine 668. This antibody has been meticulously developed and rigorously validated to ensure optimal performance and reliability in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The APP(Phospho-Thr668) Rabbit Polyclonal Antibody exhibits exceptional affinity and selectivity towards the phosphorylated form of APP at threonine 668, making it an invaluable tool for researchers studying the role of APP phosphorylation in various cellular processes and disease states, particularly in relation to Alzheimer's disease.

This antibody has been produced using state-of-the-art techniques and high-quality materials to ensure batch-to-batch consistency and reproducibility. It has undergone extensive quality control measures to guarantee its specificity, sensitivity, and reliability. The APP(Phospho-Thr668) Rabbit Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use, and is available in various sizes to accommodate different experimental needs.

With its exceptional performance characteristics and broad range of applications, the APP(Phospho-Thr668) Rabbit Polyclonal Antibody is an indispensable tool for researchers in the field of neuroscience and neurodegenerative diseases. Its reliable and accurate results will contribute to a deeper understanding of the molecular mechanisms underlying APP phosphorylation and its implications in disease pathology.