APOB Rabbit Polyclonal Antibody

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms| apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single| very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA)| resulting in the creation of a stop codon| and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia| normotriglyceridemic hypobetalipoproteinemia| and hypercholesterolemia due to ligand-defective apoB| diseases affecting plasma cholesterol and apoB levels.

The APOB Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Apolipoprotein B (APOB) in various biological samples. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring excellent performance and reliability.

Apolipoprotein B is a key protein involved in lipid metabolism and is primarily found in low-density lipoprotein (LDL) particles. It plays a crucial role in the transport of cholesterol and triglycerides in the bloodstream. Dysregulation of APOB levels has been associated with various cardiovascular diseases, making it an important target for research and diagnostic purposes.

The APOB Rabbit Polyclonal Antibody exhibits exceptional specificity, binding only to APOB and not cross-reacting with other proteins. This specificity allows for accurate and precise detection of APOB in complex biological samples. Additionally, the antibody demonstrates high sensitivity, enabling the detection of low levels of APOB with minimal background noise.

This antibody is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assays (ELISA). It has been extensively validated in various experimental conditions and has shown consistent and reproducible results.

The APOB Rabbit Polyclonal Antibody is supplied as a liquid formulation, allowing for easy handling and storage. It is provided in a convenient size, ensuring cost-effectiveness and minimizing waste. The antibody is manufactured under strict quality control measures to guarantee batch-to-batch consistency and optimal performance.

In summary, the APOB Rabbit Polyclonal Antibody is a reliable and efficient tool for the detection and quantification of APOB in biological samples. Its exceptional specificity and sensitivity, along with its versatility and ease of use, make it an invaluable asset for researchers and clinicians in the field of lipid metabolism and cardiovascular diseases.