BT Lab
SKU:BT-AP00472
CREB-1(Phospho Ser133) Polyclonal Antibody
CREB-1(Phospho Ser133) Polyclonal Antibody
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This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element| an octameric palindrome. The protein is phosphorylated by several protein kinases| and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.
The CREB-1(Phospho Ser133) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated CREB-1 at Ser133 residue. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reliability.
The phosphorylation of CREB-1 at Ser133 plays a crucial role in various cellular processes, including gene expression, neuronal plasticity, and memory formation. By targeting this specific phosphorylation site, the CREB-1(Phospho Ser133) Polyclonal Antibody enables researchers to investigate the activation and regulation of CREB-1 signaling pathway with high precision and accuracy.
This antibody exhibits exceptional sensitivity and specificity, allowing for reliable detection of phosphorylated CREB-1 in various sample types, including cell lysates, tissue extracts, and biological fluids. It is compatible with a wide range of experimental techniques, such as Western blotting, immunohistochemistry, and immunofluorescence, facilitating versatile applications in both basic research and clinical studies.
The CREB-1(Phospho Ser133) Polyclonal Antibody is supplied as a liquid formulation, ensuring ease of use and convenience. It is provided in a ready-to-use format, eliminating the need for time-consuming and error-prone antibody preparation steps. The antibody is also available in different sizes to accommodate various experimental requirements.
With its exceptional performance and reliability, the CREB-1(Phospho Ser133) Polyclonal Antibody is an indispensable tool for researchers studying CREB-1 signaling pathway and its implications in various physiological and pathological conditions. Its high specificity and sensitivity make it an ideal choice for accurate and reproducible results, enabling advancements in the understanding of cellular processes and the development of novel therapeutic strategies.
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