ANO3 Rabbit Polyclonal Antibody

The protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins| that are also known as anoctamins. While little is known about the function of this gene| mutations in this gene have been associated with some cases of autosomal dominant craniocervical dystonia. Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat show that the rat ortholog of this protein interacts with| and modulates the activity of a sodium-activated potassium channel. Deletion of this gene caused increased pain sensitivity in the rat model system. Alternative splicing results in multiple transcript variants encoding different isoforms.

The ANO3 Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of ANO3 protein expression in various biological samples. This antibody has been rigorously tested and validated to ensure its reliability and accuracy in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting applications.

ANO3, also known as Anoctamin 3, is a member of the Anoctamin family of proteins. It plays a crucial role in various physiological processes, including calcium-activated chloride channel activity and regulation of neuronal excitability. Dysregulation of ANO3 has been implicated in several neurological disorders, making it an important target for research and therapeutic development.

The ANO3 Rabbit Polyclonal Antibody has been developed using high-quality rabbit polyclonal antibodies that specifically recognize ANO3 protein. It exhibits excellent sensitivity and specificity, enabling accurate detection and quantification of ANO3 expression levels in different tissues and cell types.

This antibody has been extensively validated using a wide range of experimental techniques, including IHC, IF, and western blotting. It has shown consistent and reliable performance in detecting ANO3 protein in various species, including human, mouse, and rat.

The ANO3 Rabbit Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex antibody preparation procedures.

With its exceptional specificity, sensitivity, and versatility, the ANO3 Rabbit Polyclonal Antibody is an indispensable tool for researchers studying ANO3 protein expression and its role in various biological processes. Its reliable performance and ease of use make it an ideal choice for both basic research and clinical applications.